Association of Pasteurella multocida toxin with vimentin.
نویسندگان
چکیده
To help understand the molecular mechanisms of Pasteurella multocida toxin (PMT) action, we searched for a cellular protein interacting with PMT. The ligand overlay assay revealed a 60-kDa cellular protein that binds to a region from the 840th to 985th amino acids of the toxin. This protein was identified as vimentin by peptide mass fingerprinting. The N-terminal head domain of vimentin was further found to be responsible for the binding to the toxin.
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ورودعنوان ژورنال:
- Infection and immunity
دوره 70 11 شماره
صفحات -
تاریخ انتشار 2002